DZNE Alzheimer’s study: A Mediterranean diet might protect against memory loss and dementia

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Bonn (Germany), May 5th, 2021. Alzheimer’s disease is caused by protein deposits in the brain and the rapid loss of brain matter. But a Mediterranean diet rich in fish, vegetables and olive oil might protect the brain from these disease triggers. Experts from the DZNE report on this in a recent study. Their findings are published in the May 5, 2021 online issue of Neurology®, the medical journal of the American Academy of Neurology.

In Alzheimer’s disease, neurons in the brain die. Largely responsible for the death of neurons are certain protein deposits in the brains of affected individuals: So-called beta-amyloid proteins, which form clumps (plaques) between neurons, and tau proteins, which stick together the inside of neurons. The causes of these deposits are as yet unclear. In addition, a rapidly progressive atrophy, i.e. a shrinking of the brain volume, can be observed in affected persons. Alzheimer’s symptoms such as memory loss, disorientation, agitation and challenging behavior are the consequences.

Scientists at the DZNE led by Prof. Michael Wagner, head of a research group at the DZNE and senior psychologist at the memory clinic of the University Hospital Bonn, have now found in a study that a regular Mediterranean-like dietary pattern with relatively more intake of vegetables, legumes, fruit, cereals, fish and monounsaturated fatty acids, such as from olive oil, may protect against protein deposits in the brain and brain atrophy. This diet has a low intake of dairy products.